CENTRAL ASIAN JOURNAL OF NEPHROLOGY

The Central Asian Journal of Nephrology (ISSN 3105-4145) aims to provide a platform for the dissemination of high-quality research, clinical studies and expert opinions in the field of nephrology. It is dedicated to improving the understanding, prevention, diagnosis and treatment of kidney diseases in Central Asia and beyond. The journal aims to promote collaboration between researchers, clinicians and healthcare professionals to address the unique challenges in nephrology faced by the Central Asian region, because of its same cultural and environment factors, genetic background and similar healthcare models.

 

Call for Publications

The Central Asian Journal of Nephrology invites researchers from all over the world, clinicians, healthcare professionals, and policymakers to submit manuscripts that contribute to advancing knowledge and practice in nephrology, accommodating its regional focus and the specialized field of nephrology, while ensuring relevance to both local and international audiences.

We welcome original research, reviews, case reports, and methodological papers that explore all aspects of kidney health and disease. Topics of interest include, but are not limited to:

  • Prevention, diagnosis, and management of acute and chronic kidney diseases
  • Dialysis and renal transplantation
  • Basic science research in nephrology
  • Epidemiological studies on kidney disease burden
  • Public health and policy innovations in nephrology
  • Applications of data science, digital health, and AI in nephrology
  • Real-world evidence, patient-centered outcomes, and healthcare equity

The journal seeks to disseminate high-quality, interdisciplinary research that enhances clinical practice, informs policy, and promotes kidney health across Central Asia and beyond.

We encourage submissions that reflect regional insights, cross-national collaborations, and innovative approaches to addressing the growing challenges of kidney diseases.

Submit your manuscript today and join us in shaping the future of nephrology in Central Asia and beyond.

 

 

 

CURRENT ISSUE

Volume 1, Issue 2, 2025

(Ongoing)

Case Report
Acute Tubulointerstitial Nephritis in a Patient Post-Renal Transplantation
Central Asian Journal of Nephrology, 1(2), 2025, cajn006, https://doi.org/10.63946/cajn/16982
ABSTRACT: A 41-year old female patient who underwent kidney transplantation as an outcome of chronic glomerulonephritis came to the hospital with the signs of acute upper respiratory tract infection. As the patient further developed oliguria, peripheral edema, fever, and an increased BP, she was further relocated to the University Medical Center (UMC). Upon admission to UMC, signs of septic shock were detected, and acute transplant rejection was suspected, to exclude which kidney biopsy was performed and stage 3 chronic kidney disease (CKD) in allograft kidney was detected. Antibacterial treatment as well as pulse therapy were performed as patient had septic shock and tubulointerstitial nephritis (TIN).
Original Article
Population-Based Screening during World Kidney Day in Kazakhstan: Prevalence and Risk Factors of Reduced Renal Function
Central Asian Journal of Nephrology, 1(2), 2025, cajn007, https://doi.org/10.63946/cajn/17084
ABSTRACT: Background: Chronic kidney disease (CKD) is a major global health challenge, yet population-based data from Central Asia are scarce. We conducted a population-based screening study to assess kidney function distribution and associated risk factors in Astana, Kazakhstan.
Methods: In March 2024, 636 adults were screened through convenience sampling at four major institutions in Astana. After excluding incomplete data, 569 participants were analyzed. Demographic, lifestyle, and clinical information were collected, and serum creatinine was used to estimate glomerular filtration rate (eGFR). Reduced renal function was defined as eGFR <90 mL/min/1.73 m². Group comparisons and logistic regression analyses were performed to identify risk factors for reduced renal function.
Results: The median age of participants was 46 years (IQR 33–55), and 79.8% were women. Median eGFR was 92.8 (IQR 79.8–111.3) mL/min/1.73 m²; 54.1% had eGFR ≥90, 42.4% had eGFR 60–89, and 3.5% had eGFR 45–59. Reduced renal function was more common among older adults, females and those with hypertension and heart failure. In multivariable analysis, older age and female sex were independent predictors of reduced renal function. Awareness was low: only 15.0% of individuals with eGFR 45–59 reported having CKD.
Conclusion: This study provides the population-based evidence on kidney function in Astana, Kazakhstan. Reduced renal function was common, particularly among older adults. Findings highlight the importance of population-based screening and targeted prevention strategies to address kidney health in Kazakhstan.